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Why Does Xarelto Cause Lower Back Pain

Some Side Effects Can Be Serious If You Experience Any Of These Symptoms Or Those Listed In The Important Warning Section Call Your Doctor Immediately:

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  • bloody, black, or tarry stools
  • pink, or brown urine
  • coughing up or vomiting blood or material that looks like coffee grounds
  • frequent nosebleeds
  • pain in arm or leg
  • rash
  • hives
  • pain or swelling at wound sites

Rivaroxaban prevents blood from clotting normally so it may take longer than usual for you to stop bleeding if you are cut or injured. This medication may also cause you to bruise or bleed more easily. Call your doctor right away if bleeding or bruising is unusual.

Rivaroxaban may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration’s MedWatch Adverse Event Reporting program online or by phone .

What Are Some Things I Need To Know Or Do While I Take This Drug

  • Tell all of your health care providers that you take this drug. This includes your doctors, nurses, pharmacists, and dentists. This drug may need to be stopped before certain types of surgery as your doctor has told you. If this drug is stopped, your doctor will tell you when to start taking this drug again after your surgery or procedure.
  • You may bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor. Rarely, some bleeding problems have been deadly.
  • If you fall or hurt yourself, or if you hit your head, call your doctor right away. Talk with your doctor even if you feel fine.
  • Have blood work checked as you have been told by the doctor. Talk with the doctor.
  • If you are 65 or older, use this drug with care. You could have more side effects.
  • Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.

Why Is This Medication Prescribed

Rivaroxaban is used to treat deep vein thrombosis and pulmonary embolism . Rivaroxaban may be continued to prevent DVT and/or PE from happening again after initial treatment is completed. It is also used to help prevent strokes or serious blood clots in people who have atrial fibrillation without heart valve disease. Rivaroxaban may reduce the risk of DVT, which can lead to PE in people who are having hip replacement or knee replacement surgery. It is also used along with aspirin to lower the risk of a heart attack, stroke, or death in people with coronary artery disease or peripheral arterial disease . Rivaroxaban is in a class of medications called factor Xa inhibitors. It works by decreasing the clotting ability of the blood.

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Is There A Specific Dosage Of Xarelto For Older Adults

No, there isnt a specific dosage of Xarelto for older adults. The dosages for older adults are generally the same as those for younger adults.

However, older people may have certain health conditions that affect their dosage of Xarelto. For example, older people may have a higher risk for kidney problems that could lead to a dosage adjustment.

If youre an older adult with questions about what dosage of Xarelto is right for you, talk with your doctor.

Xarelto For Reducing The Risk Of Stroke And Blood Clots In People With A

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Xarelto is FDA-approved to reduce the risk of strokes and blood clots in people with atrial fibrillation thats not caused by a heart valve problem.

A-fib is a type of irregular heartbeat. It can disrupt the flow of blood around your body and increase your risk of having a blood clot. Blood clots can sometimes be dangerous. For example, a blood clot that travels to your brain can cause a stroke.

Xarelto is an anticoagulant . It lowers your risk of having strokes and blood clots.

Effectiveness for reducing the risk of stroke and blood clots in people with A-fib

One clinical study found Xarelto was as effective as warfarin in preventing stroke and blood clots in people with A-fib.

In this study, 3.8% of people taking Xarelto had a stroke or blood clot. In comparison, 4.3% of patients taking warfarin had a stroke or blood clot.

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Some Potentially Serious Bleeding Problems Can Occur While Taking Xarelto Contact Your Healthcare Provider Right Away If You Develop Problems Like Unusual Bruising Blood In The Urine Or Coughing Up Blood In Most Cases Side Effects Of Xarelto Tend To Be Minor And Easily Treated Common Reactions May Include Itching Elevated Liver Enzymes And Back Pain

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How Acetaminophen Is Used For Back Pain

Acetaminophen is sold in varying strengths without a prescription, including regular strength, extra strength, and arthritis pain formulas. While over-the-counter acetaminophen is often recommended to treat mild to moderate pain, a physician may recommend an acetaminophen-opioid combination in some situations, such as for severe pain or pain following back surgery.

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What Do I Do If I Miss A Dose

15 mg twice daily dosing:

  • Take missed dose right away to make sure you get 30 mg in one day. You may take 2 tablets at the same time. Then go back to your normal times the next day.
  • If you do not think about the missed dose until the next day, skip the missed dose and go back to your normal time.

2.5 mg twice daily dosing:

  • Skip the missed dose and go back to your normal time.
  • Do not take 2 doses at the same time or extra doses.

All other dosing:

  • Take a missed dose as soon as you think about it on the same day you missed the dose.
  • If you do not think about the missed dose until the next day, skip the missed dose and go back to your normal time.
  • Do not take 2 doses at the same time or extra doses.

For all patients taking this drug:

  • If you are not sure what to do if you miss a dose, call your doctor.

Dosage For People With Kidney Problems

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Before prescribing Xarelto for you, your doctor will check to see how well your kidneys are working. This allows your doctor to know whether youll need renal dosing of Xarelto. Renal dosing is a reduced dose of the drug thats typically determined by calculating your creatinine clearance.

Creatinine is a waste product thats produced by your body. Your kidneys filter creatinine out of your blood, and it exits your body through your urine. Measuring the amount of creatinine in your urine allows doctors to see how well your kidneys are working.

Usually, your doctor wont prescribe Xarelto for you to treat or prevent a DVT or PE if your creatinine clearance is lower than 15 mL/min.

However, Xarelto can be used to reduce the risk of heart attack and stroke if you have kidney problems, no matter how low your creatinine clearance is. In this case, it can also be used to reduce the risk of heart attack, stroke, and other complications from blood clots.

If you have A-fib and your creatinine clearance is 50 mL/min or less, youll need a dose reduction of the drug. In this case, the recommended dosage of Xarelto is 15 mg taken once every evening.

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Q: Are There Any Serious Xarelto Side Effects

Unfortunately, Xarelto can have an unintentionally severe impact on blood proteins, causing the blood to become extremely thin and leaving the patient susceptible to internal or external bleeding. As Xarelto is designed to prevent clotting, there is a risk that excessive bleeding may continue until Xarelto has exited the patient’s system.

Bleeding can cause serious health issues or even become fatal. For example, if there is bleeding near a vital organ such as the brain, lungs, or kidneys, then the normal blood flow to that organ may be interrupted. This disruption in the delivery of oxygen and vital nutrients could cause the organ to fail or otherwise lose some of its function.

The FDA advises that Xarelto patients tell their health care professionals if they have any signs of serious bleeding including:

  • Prolonged bleeding from wounds or gums
  • Unusual bruising
  • Abnormal menstrual flow – prolonged/heavy

Dosage For Preventing Dvt And Pe After Hip Or Knee Replacement

Xarelto is used as prophylaxis to prevent a DVT or PE following surgery done to replace your knee or hip.

For this use, youll start taking Xarelto between 6 and 10 hours after your surgery. Your healthcare professional will check to make sure that the bleeding from your surgery has stopped before you take your first dose of the drug.

Your dosage of Xarelto depends on whether youve had your hip or knee replaced. Typical dosages to prevent blood clots after these surgeries are as follows:

  • if youve had a hip replacement, the usual dosage is 10 mg taken once a day for 35 days
  • if youve had a knee replacement, the usual dosage is 10 mg taken once a day for 12 days

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Dosage For Reducing The Risk Of Recurrent Dvt Or Pe

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Xarelto is used to reduce your risk of having another DVT or PE if:

  • youve had at least 6 months of treatment for a DVT or PE with another anticoagulant drug, and
  • youre still at risk of getting another blood clot

The usual dosage of Xarelto for reducing the risk of another DVT or PE is 10 mg taken once a day.

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Should I Take My Xarelto Doses With Food

The strength of Xarelto youre prescribed will determine whether you take the drug with food.

If youre prescribed the 2.5-milligram or 10-mg Xarelto tablets, youll take your doses with or without food. If youre prescribed the 15-mg or 20-mg Xarelto tablets, youll take each dose with food.

The dosage of Xarelto youre prescribed may depend on several factors. These include:

  • the type and severity of the condition youre using Xarelto to treat
  • other conditions you may have

Your reason for taking Xarelto and the strength youre prescribed will help determine how you take the drug.

Youll likely take Xarelto either once or twice each day.

For most conditions treated with a once-daily dose of Xarelto, you can take your dose at any time of day. Try to take it at the same time each day to keep consistent levels of the drug in your body.

If youre taking Xarelto because you have atrial fibrillation , you should take your once-daily dose with your evening meal.

For conditions that require taking Xarelto twice per day, you should take one dose in the morning and one in the evening. Generally, youll separate your morning and evening doses by about 12 hours. Try to take your doses at the same times each day.

If youre taking the 2.5-mg or 10-mg Xarelto tablets, you can take your dose with or without food. But if youre taking the 15-mg or 20-mg Xarelto tablets, you should take each dose with food.

If you have questions about how to take Xarelto, talk with your doctor.

Does Xarelto Cause Leg Cramps

Clinical studies also looked at people taking Xarelto to help prevent blood clots after hip or knee replacement. In these people, 1.2% had muscle spasms. In comparison, muscle spasms occurred in 0.7% of people who took enoxaparin.In the same studies, 1.7% of people taking Xarelto had pain in their extremities.

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What Are Some Side Effects That I Need To Call My Doctor About Right Away

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash hives itching red, swollen, blistered, or peeling skin with or without fever wheezing tightness in the chest or throat trouble breathing, swallowing, or talking unusual hoarseness or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of bleeding like throwing up or coughing up blood vomit that looks like coffee grounds blood in the urine black, red, or tarry stools bleeding from the gums abnormal vaginal bleeding bruises without a cause or that get bigger or bleeding you cannot stop.
  • Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight.
  • Dizziness or passing out.
  • Feeling very tired or weak.
  • Pain, swelling, or new drainage at wound sites.

Risk Of Blood Clots If You Stop Taking Xarelto

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Xarelto has a boxed warning for risk of blood clots if you stop taking the drug. A boxed warning is a serious warning from the Food and Drug Administration . It alerts doctors and patients about drug effects that may be dangerous.

When you stop taking Xarelto, your risk for having a blood clot increases. If you have a condition that affects your arteries or heart, stopping Xarelto also increases your risk for heart attack and stroke. Examples of these conditions include peripheral artery disease and coronary artery disease.

Symptoms of a blood clot vary depending on the location of the clot and may include:

  • pain and swelling, which can affect a specific area of the body, such as the calf
  • trouble breathing
  • nausea
  • lightheadedness

For more information about this warning, see Xareltos drug label information. You can also talk with your doctor.

What you can do

You shouldnt stop taking Xarelto unless your doctor instructs you to do so.

Sometimes, you may need to temporarily stop taking Xarelto, with your doctors approval. This may be recommended before certain dental, medical, or surgical procedures. Your doctor will give you specific dates for when to stop taking Xarelto and when to start taking it again after your procedure. And, in the time leading up to your procedure, your doctor may prescribe a medication other than Xarelto for your condition.

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Can Xarelto Affect The Liver

Its not likely. Liver-related side effects werent seen in people taking Xarelto in clinical trials.

Since the drug was approved, there have been reports of liver-related side effects in people taking Xarelto. These side effects include liver damage and hepatitis . But its unclear how often these side effects may occur and if Xarelto may be the cause.

If you have questions about how Xarelto may affect your liver, talk with your doctor.

Warning Disclaimer Use For Publication

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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How Is Andexxa Used To Treat Xarelto Bleeding

If you develop severe bleeding, your doctor may treat it with an injection of a drug called Andexxa. This drug works to stop Xarelto from preventing blood clot formation in your body. Its used to treat severe, uncontrolled, or life threatening bleeding in people taking drugs such as Xarelto. Note: Xarelto has a boxed warning

Will I Need To Use This Drug Long Term

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You might, but it depends on why youre taking Xarelto. The length of time Xarelto treatment is used is based on why youre taking the drug. Typical treatment lengths are as follows:

  • If youre taking Xarelto after having a knee replacement, youll take the drug for 12 days after your surgery.
  • If youre taking Xarelto after having a hip replacement, youll take the drug for 35 days after your surgery.
  • If youre taking Xarelto because you were admitted to a hospital for an acute illness, youll take the drug for 31 to 39 days.
  • If youre taking Xarelto to treat a deep vein thrombosis or pulmonary embolism , youll take the drug for 6 to 12 months.

However, when its prescribed to prevent blood clots or their complications, Xarelto is meant to be used as a long-term treatment. If you and your doctor determine that Xarelto is safe and effective for you, youll likely take it long term for these purposes.

If you have coronary artery disease or peripheral artery disease , youll take Xarelto with aspirin.

With CAD, you have narrowed arteries in your heart. With PAD, you have narrowed arteries in your legs. Both of these conditions increase your risk of having blood clots that can cause a heart attack or stroke.

Using a combination of Xarelto and aspirin is more effective for preventing heart attack and stroke in people with CAD or PAD than using aspirin alone.

The recommended dosage of aspirin for this use is 75 mg to 100 mg taken once a day.

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