Ibuprofen Can Interact With Medications
Youre more prone to negative effects if youre taking other medications that ibuprofen doesnt mix well with.
Ibuprofen can interact with the meds youre on, especially high blood pressure medications, which can lead to some serious adverse effects, Dr. Morgan says. That could be deadly.
Ibuprofen can interact negatively with:
- Heart medication, such as clopidogrel.
- Immunosuppressive medication, such as cyclosporine.
- Seizure medication, such as phenytoin.
- Other NSAIDs.
Ibuprofen can impact certain conditions
You should also check with your doctor before taking ibuprofen if you have any of the following conditions:
- Gastrointestinal problems, including heartburn.
How much ibuprofen is safe?
How much ibuprofen you can take depends on, well, you. Theres not really a one-size-fits-all answer, Dr. Morgan says. It depends on your general state of health.
As a general rule, though, Dr. Morgan says most healthy people those who dont have high blood pressure or gastrointestinal issues can typically take ibuprofen on a limited basis to address minor aches and pains.
Its not without risk, but you can feel pretty safe taking it for about three days, she says. Take no more than 400 to 600 milligrams, three times a day, with food. Otherwise, it can ruin your stomach.
Risks Of Mixing The Two
Acetaminophen and ibuprofen are safe to take together for most people. Possible risks of combining the two include taking more than the recommended dosage by accident.
Acetaminophen and ibuprofen are present in a range of pain relief, cold, and flu medications. Their presence in these OTC products can make it easy to take more than necessary by accident.
People should take care to read medication labels to check which drugs each product contains. Carefully checking the dose of acetaminophen and ibuprofen in each product can help avoid an accidental overdose.
Symptoms of an acetaminophen overdose include the following:
- nausea and vomiting
A Move Away From Oral Painkillers
People with back pain are usually told by their health care practitioners to take analgesic medications to relieve their pain.
Out of date Australian guidelines for managing back pain recommend paracetamol as first choice analgesic, NSAIDs as second, and oral opioids as the third line medicines. Paracetamol is still the most purchased over-the-counter painkiller in Australia, but weve shown it to be ineffective for back pain.
The UK 2017 National Institute for Health and Care Excellence guidelines now no longer recommend paracetamol as a stand-alone intervention for back pain. In the UK, NSAIDs are recommended as the analgesic of first choice for back pain, and opioids as second.
However in research published last week, we show NSAIDs like ibuprofen and diclofenac offer only marginal relief from back pain compared to a placebo . Only one in six patients treated with NSAIDs achieved any significant reduction in pain.
We also found people taking NSAIDs are more than twice as likely to experience vomiting, nausea, stomach ulcers or bleeding compared to those taking placebo.
The study raises the question of whether the benefits of NSAIDs outweigh the risk of side effects offered by these drugs.
These results were obtained by reviewing 35 studies of 6,065 people with various types of spinal pain, including lower back pain, neck pain and sciatica .
Read Also: Can Uc Cause Back Pain
What Is Ibuprofen Used For
The Food and Drug Administration has approved ibuprofen for:
- Fever reduction
- Relief of minor aches and pains in muscles, bones, and joints, body pain, backache, and muscle sprains and strains
- Pain from inflammation associated with conditions, including rheumatoid arthritis and osteoarthritis
- Primary dysmenorrhea
- Aches and pains due to the common cold and flu
Take ibuprofen with food or milk to decrease the chance of stomach upset.
Ibuprofen May Cause Side Effects Tell Your Doctor If Any Of These Symptoms Are Severe Or Do Not Go Away:
Ibuprofen may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration’s MedWatch Adverse Event Reporting program online or by phone .
Don’t Miss: Does Constipation Cause Back Pain
Can I Take Ibuprofen With Ajovy
There are no known drug interactions between Ajovy and ibuprofen , but you should talk to your doctor before you combine these medications. Serious side effects can occur with ibuprofen, such as stomach or intestinal bleeding, rash, swelling, problems with your kidneys, or an increased risk of heart attack and stroke.
Ajovy is used to help prevent migraine episodes in adults. Ibuprofen is an over-the-counter analgesic used as an acute treatment to help stop migraine pain already in progress. If Ajovy is not adequately helping your migraine, your doctor may want to switch you to a different migraine prevention medicine or drug class.
When You Take Ibuprofen Every Day This Is What Happens To Your Body
Ibuprofen is one of the most common medications on the market. In fact, chances are you have a bottle or two of ibuprofen in your medicine cabinet right now. The painkiller and anti-inflammatory is sold under a variety of brand names including Advil and Motrin, and is widely used for a variety of ailments. Whether you have a headache or a fever, ibuprofen tends to be the go-to for people looking to be pain- and fever-free.
According to WebMD, ibuprofen is classified as a nonsteroidal anti-inflammatory drug more commonly known as an NSAID. NSAIDs work by stopping your body from producing substances that cause inflammation, which subsequently causes pain, swelling, and fever to dissipate. Since most forms of ibuprofen can be purchased over the counter without a prescription, the medicine is largely believed to be safe. However, ibuprofen doesn’t come without its risks some of which can be life-threatening when not treated.
As it turns out, there are more than a few ways in which your body can react negatively to ibuprofen, especially if you take too much of it on a daily basis. Here’s what happens to your body when you take ibuprofen every day.
Recommended Reading: What To Buy For Lower Back Pain
What Is Naproxen Used For
Naproxen is used to relieve a variety of conditions, such as:
- Sports injuries
- Pain from arthritis
This list is not exhaustive. Ibuprofen can be used to help with lots of different problems and conditions which cause pain and inflammation.
Ibuprofen can also be used by children as well as adults. The appropriate dosage for your child will depend on their age and size, so it is important to read the label and use it as instructed . For young children, Ibuprofen can be given as a liquid syrup which makes it easier to swallow.
What You Really Need To Know About Your Lower Back Pain
If you have no known contraindications to NSAIDs, over-the-counter weight-dosed ibuprofen is your best bet to treat acute low back pain.
But consider non-medication options as well and take an active role in your recovery from acute low back pain. Always consult your doctor before starting a new medication or supplement.
Everyone puts hydrogen peroxide on their wounds:They really shouldn’t.
Many people take melatonin:What you should know before you do
Michael Daignault, MD, is a board-certified ER doctor in Los Angeles. He studied Global Health at Georgetown University and has a Medical Degree from Ben-Gurion University. He completed his residency training in emergency medicine at Lincoln Medical Center in the South Bronx. He is also a former United States Peace Corps Volunteer. Find him on Instagram @dr.daignault
Recommended Reading: How To Get Rid Of Epidural Back Pain
Whats The Typical Dosage
Over-the-counter ibuprofen is typically available in 200-milligram pills.
Its best to use the minimum dosage necessary to relieve your symptoms. Typically, one ibuprofen pill is taken by mouth every 4 to 6 hours. If one pill doesnt work to ease symptoms, a second pill can be taken.
Dont take more than 1,200 mg of ibuprofen in one day. For OTC ibuprofen, this equates to a maximum of 6 pills per day.
Additionally, avoid taking ibuprofen for longer than 10 days, unless directed to do so by your doctor.
Back In Action: Updated Treatment Recommendations For Lower Back Pain
That dull ache when you go for your morning jog. A sharp pain when you lift a heavy box. For some people, back pain is just an annoyance that comes and goes. For others, it can be a devastating hindrance to everyday life.
Back pain affects 80 percent of people at some point in their lifetime. Each year, lower back pain causes about 149 million lost days of work in the U.S. and costs $100 billion to $200 billion mostly in lost wages and productivity.As The New York Times reported in February 2017, the American College of Physicians and the American Pain Society have released updated back pain treatment guidelines that are similar to the evidence-based approaches weve used at UT Southwestern for many years. Many people expect their pain to be treated with a doctors visit and a prescription for medication. But we know thats not how back pain works. And with an opioid epidemic ragingin America, prescribing medication as a first-line treatment for back pain is not the safest approach for patients.
Lower back pain often can be resolved by staying active without pain medication. But there are times when thats not enough. Lets discuss when you might need to visit the doctor and when back pain is manageable at home.
Also Check: Why Do I Have Sharp Lower Back Pain
How To Take Ibuprofen Responsibly
Dr. Morgan lays out a few important, commonsense guidelines to keep in mind before heading to the medicine cabinet and diving into that bottle of ibuprofen.
Nsaids Increase The Risk Of Cardiovascular Side Effects
Another worrying side effect of some NSAIDs is an increased risk of cardiovascular events such as a heart attack. Research has identified that those NSAIDs that have more of a tendency to block COX-2 compared to COX-1 have an increased risk of thrombosis . Aleve does not appear to be associated with an increased risk of detrimental vascular events, and experts tend to prefer NSAIDs that contain naproxen for this reason. Low-dose ibuprofen is considered an alternative to naproxen however, higher dosages of ibuprofen are associated with a higher risk of cardiovascular events. People who have already had a heart attack or stroke must use NSAIDs with caution. One study showed that even one or two doses of ibuprofen or diclofenac increased the risk of another event. During the 14 weeks of the study, naproxen did not appear to increase this risk. However, NSAIDS should not be used after coronary artery bypass graft surgery and all NSAIDS carry a warning that they can increase the risk of cardiovascular events, so should only be used under a doctor’s supervision, particularly in people with a history of heart disease. Reassuringly, the risk of a cardiovascular event such as a heart attack, stroke, or death is extremely small when NSAIDs are prescribed for short periods of time – such as for a musculoskeletal injury – in people at low cardiovascular risk.
Don’t Miss: Will Midol Help With Back Pain
Your Body Will Be At An Increased Risk Of A Stroke If You Take Ibuprofen Every Day
Even though ibuprofen is sold over the counter and you don’t need a prescription for the drug, it shouldn’t be taken lightly. Unless your doctor has specifically told you to take a certain amount each day, it’s best to stick to whatever the bottle recommends. This is because one of the biggest risks of taking ibuprofen every day is that you’ll be at an increased risk of having a stroke.
According to Mayo Clinic, non-steroidal anti-inflammatory drugs increase your stroke risk. Because of that, it’s of utmost importance to only take the amount you need and it’s especially important to try not to take the medication every day. While it’s clear that NSAIDs increase the body’s risk of having a stroke, there really isn’t a clear indication of why that is, as Mayo Clinic reports.
All things considered, it’s better to be safe than sorry and stick to the recommended dosage when it comes to ibuprofen. After all, if you take ibuprofen every day, you’re only putting your body even more at risk for having a stroke and no one wants that.
Other Treatments And Activities That Dont Help
Other treatment options including acupuncture, ultrasound, electrical nerve simulation, and corsets or foot orthotics are not recommended, since there is no strong evidence supporting their use.
Even if the cause of back pain is unknown, imaging is unlikely to influence management or provide meaningful information.
What About Taking Ibuprofen Before Exercise
You may be tempted to try to prevent exercise pain by taking ibuprofen or other medications before you start your activity. Experts say this isn’t a good idea. Aside from the side effects that you might experience from taking medications, research shows that taking ibuprofen before exercise may worsen damage to your body’s tissues and delay healing.
Taking Ibuprofen Every Day Isn’t Exactly Great For Your Liver
Ibuprofen may be your best friend when a headache hits, but the NSAID definitely isn’t your liver’s pal.
The health of your liver is obviously important, as it’s one of the body’s largest and most vital organs. And while there are plenty of things you can do to boost your liver’s health, not taking ibuprofen every day could just be one of the most helpful things you could possibly do for your liver. According to experts, if you take ibuprofen every day, you’re actually doing your liver a major disservice.
In fact, a 2020 study published in Scientific Reports found that ibuprofen can permanently damage the liver. “Overall, our data indicate that moderate doses of ibuprofen can affect liver more significantly than previously reported and include proteasome dysfunction, increased levels of H2O2, impaired glycolytic pathways and altered fatty acid synthesis and oxidation,” the study concluded. The increased levels of hydrogen peroxide can damage the liver, according to researchers who spoke with Medical News Today. As the researchers emphasized, it’s best to steer clear of ibuprofen unless absolutely necessary, despite its reputation of being a generally safe, over-the-counter medicine.
A Safer Alternative To Ibuprofen For Back Pain
Back pain is one of the worlds most common health problems in the world today, and it results in most cases of disability globally. It is also the most common cause of disability among younger individuals. For example, in the US, lower back pain is the leading cause of disability for those age 45 and under. A 2006 estimate was that 26 million adult Americans under the age of 65 were experiencing chronic lower back pain.
Lower back pain also leads to other problems for adults. According to researchers, not only do 28% of adults with lower back pain say that it limits what they can accomplish but lower back pain also leads to the risk of serious psychological distress being increased fourfold.
As lower back pain problems become more common, the source of the issue is becoming clear. In many cases, lower back pain is the result of long-term injuries. While a person may occasionally experience trauma that leads to immediate back problems, most people cant even identify the origin of the problem as it happened a long ago.
What Medications Are Similar
Drugs that are similar to ibuprofen and also belong to the NSAID family include:
These medications differ in the amount needed to take effect, how long they remain effective in the body, and the risks of GI toxicity.
In most cases, you should take only one NSAID at a time. Many people do continue low-dose aspirin for heart disease prevention when taking another NSAID. However, this does increase the risk of GI side effects.
Also Check: How To Prevent Lower Back Pain When Running
How Acute Lower Back Pain Is Usually Treated In The Er
Typically, doctors look inside the medicine cabinet to treat acute lower back pain. So what are the current options?
Multiple studies have looked at the effectiveness of treatment options for acute low back pain, including acetaminophen , nonsteroidal anti-inflammatory drugs like ibuprofen , narcotics like oxycodone, and muscle relaxers, or a combination thereof.
Everyone is talking about biotin:Here’s what you need to know.
A British Medical Journal meta-analysis of 13 studies including 5,400 patients found that acetaminophen was ineffective at reducing back pain. In fact, the study found that patients taking acetaminophen were four times more likely to have abnormal liver function tests, a possible side effect of long-term acetaminophen use.
Treatment with NSAIDs in the ER performed better ibuprofen, ketorolac and diclofenac all proved effective in reducing low back pain in one randomized-control study. However, the addition of a muscle relaxer to ibuprofen did not generate improvement in low back pain symptoms or mobility, according to a 2019 study in Annals of Emergency Medicine. And prior studies found no benefit to adding narcotics or the muscle relaxer diazepam to NSAIDs.
So NSAIDs perform the best in treating acute low back pain in adults.
Patients typically underdose ibuprofen aim for approximately 10mg/kg every eight hours with food as needed for pain. For an average adult, thats 600mg-800mg each dose.